SCHEMBL21708843

SCHEMBL21708843

CN(C)c1ccc(OCCN(CCO)CCO)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.55
PTGES O14684 1/20 0.47
HDAC1 Q13547 1/20 0.47
EBP Q15125 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
MCL1 Q07820 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CHKA P35790 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
MCHR1 Q99705 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12646538 0.83 APP (0.68) APPPTGESHDAC1KDM4EALDH1A1
SCHEMBL595602 0.82 APP (0.61) APPPTGESHDAC1KDM4EALDH1A1
SCHEMBL56046 0.80 HRH3 (0.63) APPKDM4EALDH1A1HRH3
SCHEMBL8391003 0.79 APP (0.50) APPEBPSIGMAR1ALDH1A1MAPT
SCHEMBL1333744 0.78 ALDH1A1 (0.63) EBPSIGMAR1KDM4EALDH1A1MAPT
SCHEMBL22831345 0.78 ALDH1A1 (0.63) EBPSIGMAR1KDM4EALDH1A1MAPT
Trolamine SCHEMBL9471496 0.76 ALDH1A1 (0.62) APPKDM4EALDH1A1MAPTTSHR
SCHEMBL9020577 0.76 APP (0.54) APPPTGESHDAC1KDM4EALDH1A1
SCHEMBL13406730 0.76 APP (0.55) APPPTGESHDAC1KDM4EALDH1A1
SCHEMBL14948221 0.75 SLC2A1 (0.59) APPPTGESHDAC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11204553-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-21 US disclosed
US-20200050104-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed