Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140756 | 0.82 | NPC1 (0.47) | ALDH1A1MAPTRAB9A | |
| SCHEMBL1263730 | 0.81 | PTGES (0.68) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL1263098 | 0.81 | ALDH1A1 (0.62) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL19958267 | 0.81 | APP (0.70) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL56046 | 0.79 | HRH3 (0.63) | APPALDH1A1KDM4E | |
| SCHEMBL12646538 | 0.79 | APP (0.68) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL11774712 | 0.79 | APP (0.54) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL25363203 | 0.78 | L3MBTL1 (0.48) | APPALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL595602 | 0.78 | APP (0.61) | APPPTGESHDAC1CHKAALDH1A1 | |
| SCHEMBL11020409 | 0.78 | APP (0.57) | APPPTGESHDAC1CHKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301119-A | Novel indenone derivatives and use thereof | 淀粉样蛋白解决方案株式会社 | 2025-01-10 | — | — | CN | disclosed |
| US-5532138-A | Method and kits for determining peroxidatively active catalysts | BEHRINGWERKE AG (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5445944-A | Reacting with hydrogen donor | SYNTEX (U.S.A.) INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5332662-A | Methods for determining peroxidatively active substances | SYNTEX (U.S.A.) INC. (US) | 1994-07-26 | — | — | US | disclosed |