SCHEMBL21708867

SCHEMBL21708867

C#CCNCC(OCC#C)c1ccc2c(c1)OC(C)(C)O2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
TSHR P16473 1/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21708929 0.81
SCHEMBL21708863 0.80 ALOX15 (0.31) ALOX15ALOX12TSHR
SCHEMBL21709154 0.80 TSHR (0.30) TSHR
SCHEMBL21708868 0.76 MAPT (0.41) ALOX12TSHR
SCHEMBL21709067 0.74 KDM1A (0.34) TSHRKDM1A
SCHEMBL21709065 0.72 MAOA (0.40) TSHRKDM1A
SCHEMBL21708850 0.67 ALOX15 (0.42) ALOX15ALOX12TSHR
SCHEMBL11864900 0.65 AOC3 (0.42) KDM1A
SCHEMBL11871569 0.65 CYP1A2 (0.46)
SCHEMBL21708928 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed