Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21709065 | 0.88 | MAOA (0.40) | KDM1AMAOBMAOAHTR2ATSHR | |
| SCHEMBL21709053 | 0.82 | KDM1A (0.40) | KDM1AMAOBMAOAKMT2AHTR2A | |
| SCHEMBL21709063 | 0.80 | MAOB (0.36) | MAOBMAOAKMT2AHTR2AHPGD | |
| SCHEMBL21709215 | 0.80 | KDM1A (0.30) | KDM1A | |
| SCHEMBL21708868 | 0.80 | MAPT (0.41) | MAOAKMT2AHPGDTSHRLMNA | |
| SCHEMBL21709216 | 0.79 | MAOA (0.32) | KDM1AMAOBMAOA | |
| SCHEMBL21709246 | 0.77 | KDM1A (0.32) | KDM1A | |
| SCHEMBL21709059 | 0.76 | MAOB (0.32) | MAOBMAOAHPGDTSHRLMNA | |
| SCHEMBL21708867 | 0.74 | ALOX15 (0.32) | KDM1ATSHR | |
| SCHEMBL21709054 | 0.72 | SLC22A3 (0.48) | KMT2AHPGDTSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020032080-A1 | COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND | 学校法人慶應義塾 | 2020-02-13 | — | — | WO | disclosed |