SCHEMBL21709147

SCHEMBL21709147

C#CCNCC(O)c1cc2c(cc1C#C)OC(C)(C)O2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709154 0.80 TSHR (0.30) TSHR
SCHEMBL21708926 0.79 ALDH1A1 (0.31) KDM1A
SCHEMBL21709159 0.78 TSHR (0.33) TSHR
SCHEMBL21709152 0.77 ADRA1A (0.41) TSHRKDM1A
SCHEMBL21709262 0.74 P2RX3 (0.38) TSHRKDM1A
SCHEMBL21708904 0.72 KDM1A (0.37) KDM1A
SCHEMBL21709191 0.72 TSHR (0.39) TSHR
SCHEMBL21709146 0.71 TSHR (0.36) TSHR
SCHEMBL21708891 0.69 KDM1A (0.35) KDM1A
SCHEMBL21709162 0.68 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed