Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 6/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531459 | 1.00 | ADAMTS4 (0.40) | ADAMTS4ADAMTS5MMP8CA12CA1 | |
| SCHEMBL7783075 | 0.77 | CA12 (0.55) | MMP8CA12CA1CA2MMP1 | |
| SCHEMBL15224176 | 0.76 | CYP2D6 (0.45) | MMP8CA12CA1CA2MMP1 | |
| SCHEMBL24287990 | 0.74 | SIGMAR1 (0.50) | ADAMTS4ADAMTS5MMP8EPHX1SIGMAR1 | |
| SCHEMBL23131808 | 0.74 | SIGMAR1 (0.50) | ADAMTS4ADAMTS5MMP8EPHX1SIGMAR1 | |
| SCHEMBL18430288 | 0.74 | SIGMAR1 (0.50) | ADAMTS4ADAMTS5MMP8EPHX1SIGMAR1 | |
| SCHEMBL23902745 | 0.74 | SIGMAR1 (0.50) | ADAMTS4ADAMTS5MMP8EPHX1SIGMAR1 | |
| SCHEMBL18823181 | 0.74 | SIGMAR1 (0.50) | ADAMTS4ADAMTS5MMP8EPHX1SIGMAR1 | |
| SCHEMBL6538230 | 0.74 | CA12 (0.46) | MMP8CA12CA1CA2MMP1 | |
| SCHEMBL6539544 | 0.74 | CA12 (0.46) | MMP8CA12CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889561-B2 | Process of making somatostatin modulators | Crinetics Pharmaceuticals, Inc. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200048219-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048219-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | ADAMTS4 62/4885ADAMTS5 71/4885MMP8 1906/4885 |
| US-10889561-B2 | Process of making somatostatin modulators | SSTR5, SSTR4, SSTR2 | ADAMTS4 62/4885ADAMTS5 71/4885MMP8 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.