Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177479 | 0.80 | ENPP2 (0.48) | ENPP2PTGS2 | |
| SCHEMBL31238686 | 0.78 | ENPP2 (0.46) | ENPP2PTGS2 | |
| SCHEMBL7567240 | 0.78 | CA12 (0.64) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL5484562 | 0.75 | APP (0.42) | CA12CA1CA2CA9 | |
| SCHEMBL2376239 | 0.75 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL710011 | 0.75 | LOX (0.46) | ENPP2PTGS2 | |
| SCHEMBL3123896 | 0.75 | ENPP2 (0.52) | ENPP2PTGS2 | |
| SCHEMBL10452224 | 0.74 | PTGS2 (0.46) | ENPP2PTGS2 | |
| SCHEMBL2181909 | 0.74 | ENPP2 (0.47) | ENPP2 | |
| SCHEMBL803901 | 0.73 | PTGS2 (0.68) | CA12CA1CA2CA9ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346807-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010055005-A1 | NAPHTHYLACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | disclosed |