SCHEMBL5484562

SCHEMBL5484562

IC#Cc1ccc(C#CI)cc1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.42
MAPT P10636 1/20 0.35
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231360 0.85 CA2 (0.50) MAPTCA12CA1CA2CA9
SCHEMBL1231855 0.83
SCHEMBL10140594 0.79 ACACB (0.41) APP
SCHEMBL21966146 0.73 ALDH1A1 (0.37) CA12CA1CA2CA9
SCHEMBL22466110 0.71 PTPN11 (0.57) MAPTCA12CA1CA2CA9
SCHEMBL12824425 0.69 CYP1A2 (0.56) CYP1A2
SCHEMBL22230127 0.69 CHRNB2 (0.50) MAPT
SCHEMBL1306241 0.67 APP (0.47) APPMAPTCA12CA1CA2
SCHEMBL20015758 0.67 APP (0.47) APPMAPTCA12CA1CA2
SCHEMBL22666661 0.62 APP (0.36) APPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263732-B2 Photo-alignment film and liquid crystal display element JNC CORPORATION (JP) 2012-09-11 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed