Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464918 | 0.81 | ADORA3 (0.69) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL21257354 | 0.79 | ADORA3 (0.71) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL19503866 | 0.79 | ADORA3 (0.75) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL21710869 | 0.76 | ADORA3 (0.62) | ADORA3ADORA2AADORA1ADORA2BPPARD | |
| SCHEMBL19807418 | 0.76 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BHTR2B | |
| SCHEMBL16178340 | 0.73 | ADORA3 (0.73) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL13456537 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL13429434 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL13429451 | 0.71 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 | |
| SCHEMBL13456592 | 0.71 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953031-B2 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200046751-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953031-B2 | Compounds and methods for treating neurological and cardiovascular conditions | TNNI3, CPT1B, TNNT2 | ADORA3 778/4885ADORA2A 436/4885ADORA1 994/4885 |
| US-20200046751-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | TNNI3, CPT1B, TNNT2 | ADORA3 778/4885ADORA2A 436/4885ADORA1 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.