Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SORD | Q00796 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457199 | 0.80 | PIK3CA (0.55) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL244876 | 0.79 | HRH3 (0.65) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL21914804 | 0.79 | PIK3CA (0.50) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL1110658 | 0.79 | PIK3CA (0.50) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL13033968 | 0.79 | KMT2A (0.57) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL29790016 | 0.79 | PIK3CA (0.50) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL28024738 | 0.76 | HSD17B10 (0.51) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL20000530 | 0.76 | PIK3CA (0.51) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL9678255 | 0.75 | OGA (0.59) | PIK3CAPIK3CDMEN1USP2ALDH1A1 | |
| SCHEMBL3811303 | 0.75 | OGA (0.59) | PIK3CAPIK3CDMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10806738-B2 | Theramutein modulators | HMI Medical Innovations, LLC (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200046718-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10806738-B2 | Theramutein modulators | TSG101, SERPINE1, PLAUR | PIK3CA 2425/4885PIK3CD 3894/4885MEN1 552/4885 |
| US-20200046718-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | PIK3CA 2425/4885PIK3CD 3894/4885MEN1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.