Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid Methyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL29240015 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL28848665 | 0.97 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL28163789 | 0.97 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL28171454 | 0.97 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL14892886 | 0.97 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL1854813 | 0.94 | HCAR2 (0.56) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL7645157 | 0.94 | HCAR2 (0.56) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL9108 | 0.94 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL502518 | 0.92 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2LMNATSHR | |
| Acrylic Acid Methyl Ester SCHEMBL36950 | 0.92 | LMNA (0.56) | HCAR2KEAP1NFE2L2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041184-A1 | POLY(ALKYL CARBONATE) ADHESIVES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |
| US-20200056038-A1 | POLY (ALKYL CARBONATE) ADHESIVES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-02-20 | — | — | US | disclosed |
| CN-108463773-A | Radiation sensitive resin composition, resist pattern forming method and acid diffusion controlling agent | JSR株式会社 | 2018-08-28 | — | — | CN | disclosed |
| CN-104062850-A | Active Energy Radiation Ray Gel-type Resin Composition, Coloring Spacer And/or Black Matrix For Display Element Using Active Energy Radiation Ray Gel-type Resin Composition | NIPPON KAYAKU KK | 2014-09-24 | — | — | CN | disclosed |
| CN-103901720-A | Active energy ray-cured resin compound, and coloring partition and black matrix for display element | NIPPON KAYAKU KK | 2014-07-02 | — | — | CN | disclosed |
| CN-103869616-A | Active energy ray curable resin composition and spacer for display device using the same and/or color filter protective layer | NIPPON KAYAKU KK | 2014-06-18 | — | — | CN | disclosed |
| CN-103869617-A | Active radiation hardenable resin composition, and spacer and/or color filter protective layer for display element using the same | NIPPON KAYAKU KK | 2014-06-18 | — | — | CN | disclosed |
| CN-101538348-B | Active energy ray solidification type resin composition using reactivity compound with fire retardance and condensate thereof | NIPPON KAYAKU KK | 2012-11-07 | — | — | CN | disclosed |
| CN-101538348-A | Active energy ray solidification type resin composition using reactivity compound with fire retardance and condensate thereof | NIPPON KAYAKU KK | 2009-09-23 | — | — | CN | disclosed |