Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid Methyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28161361 | 0.97 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL28094174 | 0.97 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL5156014 | 0.97 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL8023545 | 0.95 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL27418477 | 0.95 | LMNA (0.50) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL14892886 | 0.94 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL27802604 | 0.92 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL29240015 | 0.92 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL21715435 | 0.92 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL3738670 | 0.92 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4170757-B1 | BINDER FOR SECONDARY BATTERY, NEGATIVE ELECTRODE FOR SECONDARY BATTERY INCLUDING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME | SK ON CO LTD (KR) | 2024-07-17 | — | — | EP | disclosed |
| CN-118165153-A | Carbon acrylic acid propylene acetic acid polymeric material for radon measurement nuclear track detection and preparation method thereof | 中国疾病预防控制中心 | 2024-06-11 | — | — | CN | disclosed |
| US-11970448-B2 | Monomers capable of dimerizing in an aqueous solution, and methods of using same | CORNELL UNIVERSITY (US) | 2024-04-30 | — | — | US | disclosed |
| CN-117836333-A | Free radically polymerizable composition, method of polymerization, and polymerized composition | 3M创新有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-11897977-B2 | Photolabile barbiturate compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-02-13 | — | — | US | disclosed |
| WO-2023166342-A1 | POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-4195327-A1 | BINDER FOR SECONDARY BATTERY, NEGATIVE ELECTRODE FOR SECONDARY BATTERY INCLUDING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME | SK Innovation Co., Ltd. (KR) | 2023-06-14 | — | — | EP | disclosed |
| US-20230127580-A1 | Binder for Secondary Battery, Negative Electrode for Secondary Battery Including the Same, and Lithium Secondary Battery Including the Same | SK ON CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| EP-4170757-A1 | BINDER FOR SECONDARY BATTERY, NEGATIVE ELECTRODE FOR SECONDARY BATTERY INCLUDING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME | SK Innovation Co., Ltd. (KR) | 2023-04-26 | — | — | EP | disclosed |
| WO-2023031719-A1 | FREE-RADICALLY POLYMERIZABLE COMPOSITION, METHOD OF POLYMERIZING THE SAME, AND POLYMERIZED COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-1990011184-A1 | METHOD OF TREATING DISCONTINUOUS FIBERS | WEYERHAEUSER COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |
| EP-0202472-B1 | NON-LAMINATED DRY FORMED ABSORBENT PRODUCT | GRAIN PROCESSING CORPORATION (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0301772-A2 | Nonwoven materials | BONAR CARELLE LIMITED (GB) | 1989-02-01 | — | — | EP | disclosed |
| EP-0202472-A1 | Non-laminated dry formed absorbent product | GRAIN PROCESSING CORPORATION (US) | 1986-11-26 | — | — | EP | disclosed |
| EP-0040923-B1 | COMPOSITIONS FOR PROVIDING ABHERENT COATINGS; POLY (FLUOROOYALKYLENE) URETHANE ACRYLATES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4383878-A | RELEASE COATING OF RADIATION CURED POLYFLUORINATED ACRYLATE MONOMER, CURING AGENT AND POLYMER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
| US-4364992-A | USED FOR SANITARY NAPKINS OR DIAPERS | KAO SOAP CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |
| US-4321404-A | Compositions for providing abherent coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0040923-A2 | Compositions for providing abherent coatings; poly (fluorooyalkylene) urethane acrylates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4144388-A | Film-forming and thermocurable vinyl alcohol-substituted acrylamide copolymers and process for production thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970448-B2 | Monomers capable of dimerizing in an aqueous solution, and methods of using same | CALCOCO2, MDN1, MBNL1 | HCAR2 2909/4885KEAP1 4353/4885NFE2L2 3577/4885 |
| US-11897977-B2 | Photolabile barbiturate compounds | PPOX, CBR1, CBR3 | HCAR2 3119/4885KEAP1 1607/4885NFE2L2 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.