SCHEMBL21717362

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21710705	0.90	PTGES (0.36)	PTGESCYP1A1CYP1A2FYNMAPK3
	SCHEMBL21710474	0.89	PTGES (0.35)	PTGESCYP1A1CYP1A2FYNMAPK3
	SCHEMBL21710472	0.89	PTGES (0.38)	PTGESCYP1A1CYP1A2FYNMAPK3
	SCHEMBL21710477	0.86	PTGES (0.34)	PTGESCYP1A1CYP1A2FYNMAPK3
	SCHEMBL22858082	0.86	KDM4E (0.36)	PTGESCYP1A1CYP1A2FYNMAPK3
	SCHEMBL22679268	0.86	PTGES (0.34)	PTGESESR1ESR2CYP1A1CYP1A2
	SCHEMBL21717849	0.85	KMT2A (0.39)	ESR1ESR2CYP1A2KDM4EKMT2A
	SCHEMBL21718006	0.83	ESR1 (0.44)	ESR1ESR2KDM4EKMT2AMEN1
	SCHEMBL22858284	0.82	ESR1 (0.38)	PTGESESR1ESR2KDM4EKMT2A
	SCHEMBL21710479	0.82	HPRT1 (0.35)	PTGESCYP1A2FYNAHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.