SCHEMBL21717532

SCHEMBL21717532

c1ccc2c(c1)oc1cc3c4cccc5c6c7c(ccc6n(c3cc12)c45)oc1ccccc17

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 5/20 0.40
HPGD P15428 5/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
AHR P35869 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 2/20 0.35
MAOA P21397 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 2/20 0.32
GAA P10253 1/20 0.32
BCAT1 P54687 1/20 0.31
GLA P06280 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717991 0.95 MAPT (0.40) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21889616 0.94 ALDH1A1 (0.37) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21889617 0.89 AHR (0.49) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21717882 0.89 AHR (0.49) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21718159 0.87 ALDH1A1 (0.39) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21717964 0.87 AHR (0.38) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21717530 0.87 AHR (0.38) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL17573734 0.86 ALDH1A1 (0.33) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL21717538 0.86 AHR (0.46) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL27013358 0.85 AHR (0.33) MAPTKDM4EALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-20200266361-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-08-20 US disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device RER1, RPS19, RPL19 MAPT 2777/4885KDM4E 1641/4885ALDH1A1 950/4885
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 MAPT 1866/4885KDM4E 2210/4885ALDH1A1 153/4885
US-20200266361-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE RER1, RPS19, RPL19 MAPT 2777/4885KDM4E 1641/4885ALDH1A1 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.