Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562891 | 0.82 | ALDH1A1 (0.42) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL29776868 | 0.82 | ALDH1A1 (0.42) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL3837700 | 0.77 | — | — | |
| SCHEMBL8983912 | 0.73 | PDCD1 (0.37) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL21722357 | 0.71 | MEN1 (0.33) | ALDH1A1HPGDMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL21722998 | 0.68 | ALDH1A1 (0.38) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL148575 | 0.68 | TSHR (0.35) | ALDH1A1CYP2A6TDP1LMNA | |
| SCHEMBL21936342 | 0.68 | TSHR (0.35) | ALDH1A1CYP2A6TDP1LMNA | |
| SCHEMBL2454734 | 0.67 | ALDH1A1 (0.46) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL5613847 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837304-A1 | CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3837305-A1 | CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3837317-A1 | CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020035149-A1 | CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035152-A1 | CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035151-A1 | CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2020-02-20 | — | — | WO | disclosed |