Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364573 | 0.89 | FFAR1 (0.55) | FFAR1L3MBTL1LMNAMAPTTDP1 | |
| SCHEMBL2169720 | 0.86 | F2RL1 (0.62) | FFAR1PARP10L3MBTL1MAPTKMT2A | |
| SCHEMBL2173032 | 0.84 | FFAR1 (0.74) | FFAR1PARP10SRD5A2LTA4HFFAR4 | |
| SCHEMBL2171661 | 0.83 | FFAR1 (0.53) | FFAR1EPHX2L3MBTL1SRD5A2KMT2A | |
| SCHEMBL2170992 | 0.83 | FFAR1 (0.53) | FFAR1EPHX2PARP10SRD5A2LTA4H | |
| SCHEMBL4653480 | 0.81 | FFAR1 (0.60) | FFAR1SRD5A2FFAR4ALDH1A1 | |
| SCHEMBL1413843 | 0.80 | F2RL1 (0.68) | FFAR1L3MBTL1MAPTALDH1A1F2RL1 | |
| SCHEMBL31238464 | 0.80 | PARP10 (0.58) | FFAR1PARP10LMNAMAPTSRD5A2 | |
| SCHEMBL661277 | 0.80 | PLAAT3 (0.51) | FFAR1L3MBTL1TDP1 | |
| SCHEMBL18462297 | 0.79 | TEAD4 (0.56) | FFAR1EPHX2MAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |