Sugi Predict

Sugi Predict / Compounds / SCHEMBL217228

SCHEMBL217228

SCHEMBL217228

O=c1[nH]c2ccc([N+](=O)[O-])cc2o1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS1 P29475 1/20 0.54
▸ GRIA1 P42261 1/20 0.54
▸ GRIA2 P42262 1/20 0.54
▸ GRIA3 P42263 1/20 0.54
▸ GRIA4 P48058 1/20 0.54
▸ PSMB8 P28062 1/20 0.51
▸ CA12 O43570 1/20 0.49
▸ CA9 Q16790 1/20 0.49
▸ PDE3B Q13370 1/20 0.47
▸ PDE3A Q14432 1/20 0.47
▸ OGT O15294 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ PARP1 P09874 2/20 0.46
▸ CTSV O60911 1/20 0.46
▸ CTSL P07711 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ CREBBP Q92793 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31187650 0.86 PSMB8 (0.69) NOS1GRIA1GRIA2GRIA3GRIA4
SCHEMBL224438 0.86 PSMB8 (0.69) NOS1GRIA1GRIA2GRIA3GRIA4
SCHEMBL13152526 0.84 NOS1 (0.61) NOS1PDE3BPDE3AOGTALDH1A1
SCHEMBL6541777 0.84 PGR (0.58) NOS1PSMB8PDE3BPDE3AALDH1A1
SCHEMBL30683873 0.81 PSMB8 (0.77) NOS1GRIA1GRIA2GRIA3GRIA4
SCHEMBL29530378 0.80 CA12 (0.58) GRIA1GRIA2GRIA3GRIA4CA12
SCHEMBL870661 0.80 CA12 (0.58) GRIA1GRIA2GRIA3GRIA4CA12
SCHEMBL31110228 0.77 PARP1 (0.58) GRIA1GRIA2GRIA3GRIA4PSMB8
SCHEMBL2062395 0.77 PARP1 (0.58) GRIA1GRIA2GRIA3GRIA4PSMB8
SCHEMBL3813431 0.77 PARP1 (0.54) GRIA1GRIA2GRIA3GRIA4PSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105018506-A Hydrolase of benzoxazolone compound, gene for coding hydrolase and engineering strain containing gene and application thereof UNIV NANJING AGRICULTURAL 2015-11-04 — — CN claimed
JP-55120572-A — — None — — JP disclosed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 — — US disclosed
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 — — US disclosed
US-20260053786-A1 FORMULATIONS OF RADIPRODIL GRIN THERAPEUTICS INC (US) 2026-02-26 — — US disclosed
EP-4680659-A1 USE OF HYDROXY SUBSTITUTED URONES AS CURE ACCELERATORS Hexcel Composites Limited (GB) 2026-01-21 — — EP disclosed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
US-12419881-B1 Methods of using radiprodil in the treatment of disorders GRIN THERAPEUTICS, INC. (US) 2025-09-23 — — US disclosed
US-20250288518-A1 METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS GRIN THERAPEUTICS, INC. 2025-09-18 — — US disclosed
US-20250288574-A1 METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS GRIN THERAPEUTICS, INC. 2025-09-18 — — US disclosed
EP-0971894-A1 NICOTINAMIDE DERIVATIVES Pfizer Products Inc. (US) 2000-01-19 — — EP disclosed
WO-1998045268-A1 NICOTINAMIDE DERIVATIVES PFIZER PRODUCTS INC. (US) 1998-10-15 — — WO disclosed
EP-0409484-B1 4,5,6,7-Tetrasubstituted benzoxazolones PFIZER (US) 1994-06-08 — — EP disclosed
US-5071863-A Antiallergens; antiinflammatory agents; enzyme inhibitors PFIZER INC. (US) 1991-12-10 — — US disclosed
EP-0409484-A2 4,5,6,7-Tetrasubstituted benzoxazolones PFIZER INC. (US) 1991-01-23 — — EP disclosed
EP-0075533-B1 HEAT-CURABLE EPOXY-RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1985-08-07 — — EP disclosed
US-4492709-A VISION DEFECTX SYNTHELABO (FR) 1985-01-08 — — US disclosed
US-4404356-A USING A 2-HYDROXYPHENYL UREA AS CORING AGENT; STORAGE STABILITY; CASTINGS; MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1983-09-13 — — US disclosed
EP-0075533-A1 Heat-curable epoxy-resin compositions CIBA-GEIGY AG (CH) 1983-03-30 — — EP disclosed
JP-S55120572-A PRODUCTION OF BENZOXAZOLONE COMPOUND NIPPON KAYAKU CO LTD 1980-09-17 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053786-A1 FORMULATIONS OF RADIPRODIL GRIN2D, GRIN2A, GRIN2B NOS1 2825/4885GRIA1 58/4885GRIA2 35/4885
US-20250288574-A1 METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS CLN6, GABARAPL2, GABARAPL1 NOS1 4459/4885GRIA1 1378/4885GRIA2 855/4885
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 NOS1 1122/4885GRIA1 3318/4885GRIA2 3966/4885
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CLIC1 NOS1 1209/4885GRIA1 617/4885GRIA2 1536/4885
US-12419881-B1 Methods of using radiprodil in the treatment of disorders CLN6, GABARAPL2, GABARAPL1 NOS1 4459/4885GRIA1 1378/4885GRIA2 855/4885
US-20250288518-A1 METHODS OF USING RADIPRODIL IN THE TREATMENT OF DISORDERS CLN6, GABARAPL2, GABARAPL1 NOS1 4459/4885GRIA1 1378/4885GRIA2 855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.