SCHEMBL21723199

SCHEMBL21723199

Cc1cc(F)c(-n2nc(SCC(F)(F)F)nc2C)cc1C(=O)O.NC(=O)c1ccccc1CC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 1/20 0.33
HCRTR2 O43614 5/20 0.32
HCRTR1 O43613 4/20 0.32
TTR P02766 1/20 0.31
TP53 P04637 1/20 0.31
F10 P00742 1/20 0.30
CYP3A4 P08684 1/20 0.30
CD38 P28907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21723603 0.73 ADORA1 (0.32) TTRF10
SCHEMBL21723595 0.69 KDM4E (0.36)
SCHEMBL21723198 0.68 TTR (0.42) GPR52TTR
SCHEMBL21723610 0.68 TTR (0.44) TTR
SCHEMBL363265 0.66 KDM4E (0.45) HCRTR2HCRTR1CYP3A4CD38
Hydrochloric Acid SCHEMBL28047477 0.65 KDM4E (0.44) HCRTR2HCRTR1CYP3A4CD38
Hydrochloric Acid SCHEMBL27491870 0.65 KDM4E (0.44) HCRTR2HCRTR1CYP3A4CD38
SCHEMBL21723237 0.62 TTR (0.41) GPR52TTR
SCHEMBL30281187 0.62 FOLH1 (0.53) HCRTR2HCRTR1TP53
SCHEMBL1349618 0.62 FOLH1 (0.53) HCRTR2HCRTR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020036133-A1 3-(1H-1,2,4-TRIAZOLE-1-YL) BENZOIC ACID AMIDE DERIVATIVE AND HARMFUL ORGANISM CONTROL AGENT クミアイ化学工業株式会社 2020-02-20 WO disclosed