Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723254 | 0.86 | HSD11B1 (0.41) | HSD11B1POLBNFE2L2PGRKDM4E | |
| SCHEMBL3634123 | 0.83 | HSD11B1 (0.39) | HSD11B1POLBNFE2L2PGRFLT1 | |
| SCHEMBL21723392 | 0.83 | MEN1 (0.42) | HSD11B1NFE2L2HTR6 | |
| SCHEMBL28563588 | 0.81 | GAA (0.38) | HSD11B1POLBKDM4ECYP3A4 | |
| SCHEMBL8764172 | 0.79 | HSD11B1 (0.38) | HSD11B1POLBPGRF2PRSS2 | |
| SCHEMBL3634119 | 0.76 | HSD11B1 (0.39) | HSD11B1POLBNFE2L2PGRKDM4E | |
| SCHEMBL8734841 | 0.75 | SMN1; SMN2 (0.41) | HSD11B1POLBPGRFLT1FLT4 | |
| SCHEMBL198294 | 0.74 | HSD11B1 (0.46) | HSD11B1NFE2L2PGRKDM4ECYP1A2 | |
| SCHEMBL8763896 | 0.73 | HCRTR2 (0.36) | HSD11B1PGRF2KDM4ECYP3A4 | |
| SCHEMBL8634554 | 0.73 | HSD11B1 (0.46) | HSD11B1NFE2L2PGRKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930345-A | Novel halo- (3- (phenylsulfonyl) prop-1-ene) pyridine derivatives and uses thereof | 韩国科学技术研究院 | 2021-06-08 | — | — | CN | disclosed |
| WO-2020036474-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | 한국과학기술연구원 | 2020-02-20 | — | — | WO | disclosed |