SCHEMBL8734841

SCHEMBL8734841

O=P(O)(O)COS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.38
HSD11B1 P28845 2/20 0.36
POLB P06746 1/20 0.36
FLT1 P17948 1/20 0.36
FLT4 P35916 1/20 0.36
KDR P35968 1/20 0.36
LMNA P02545 1/20 0.36
F2 P00734 4/20 0.36
ACP3 P15309 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ITGAV P06756 1/20 0.35
PRSS2 P07478 1/20 0.35
PGR P06401 1/20 0.35
HTT P42858 1/20 0.35
CTRC Q99895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764172 0.87 HSD11B1 (0.38) SMN1; SMN2HSD11B1POLBF2PRSS2
SCHEMBL27447647 0.84 SMN1; SMN2 (0.40) SMN1; SMN2HSD11B1POLBLMNAALDH1A1
SCHEMBL8763896 0.84 HCRTR2 (0.36) HSD11B1F2ALDH1A1PRSS2PGR
SCHEMBL8734735 0.81 SMN1; SMN2 (0.46) SMN1; SMN2GAAPOLBLMNAACP3
SCHEMBL27385499 0.81 SMN1; SMN2 (0.37) SMN1; SMN2LMNAACP3
SCHEMBL8728100 0.81 ALDH1A1 (0.41) GAAALDH1A1
SCHEMBL155629 0.80 KMT2A (0.42) GAAHSD11B1POLBLMNAACP3
SCHEMBL8731843 0.80 HSD17B10 (0.37) HSD11B1POLBLMNAF2ALDH1A1
SCHEMBL8734748 0.77 ALDH1A1 (0.36) SMN1; SMN2HSD11B1F2ALDH1A1ITGAV
SCHEMBL8763909 0.77 HSD11B1 (0.34) HSD11B1F2ALDH1A1PRSS2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
CN-1066266-A PHOSPHOSULFONATE HERBICIDES ROHM & HAAS (US) 1992-11-18 CN claimed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed