SCHEMBL8764172

SCHEMBL8764172

CP(=O)(O)COS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.38
F2 P00734 9/20 0.37
PRSS2 P07478 3/20 0.36
CTRC Q99895 4/20 0.36
HCRTR2 O43614 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
F10 P00742 1/20 0.35
PGR P06401 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734841 0.87 SMN1; SMN2 (0.41) HSD11B1F2PRSS2CTRCHTT
SCHEMBL8763896 0.85 HCRTR2 (0.36) HSD11B1F2PRSS2CTRCHCRTR2
SCHEMBL8763931 0.83 SMN1; SMN2 (0.40) SMN1; SMN2POLB
SCHEMBL8764677 0.82 MAPT (0.43) SMN1; SMN2
SCHEMBL8731843 0.80 HSD17B10 (0.37) HSD11B1F2PRSS2HCRTR2HTT
SCHEMBL8734740 0.80 ALDH1A1 (0.35) HSD11B1F2PRSS2SMN1; SMN2PGR
SCHEMBL21723255 0.79 HSD11B1 (0.41) HSD11B1F2PRSS2HTTF10
SCHEMBL8712194 0.78 HSD11B1 (0.43) HSD11B1F2PRSS2CTRCHCRTR2
SCHEMBL8764044 0.78 SMN1; SMN2 (0.36) HTTSMN1; SMN2
SCHEMBL8734748 0.78 ALDH1A1 (0.36) HSD11B1F2PRSS2SMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP claimed