Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723420 | 0.89 | HSP90AA1 (0.46) | KDM4EALDH1A1ACHEKMT2A | |
| SCHEMBL21724251 | 0.88 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21724450 | 0.86 | TAS2R14 (0.39) | KDM4EALDH1A1TAS2R14MEN1KMT2A | |
| SCHEMBL21723953 | 0.85 | HTT (0.41) | KDM4EALDH1A1HTT | |
| SCHEMBL21723690 | 0.83 | ALDH1A1 (0.43) | KDM4EMITFALDH1A1HTTMEN1 | |
| SCHEMBL21723721 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21723580 | 0.83 | TSHR (0.47) | ALDH1A1 | |
| SCHEMBL21723880 | 0.81 | PTPN1 (0.45) | KDM4EALDH1A1HTTTAS2R14MEN1 | |
| SCHEMBL21723648 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HTTACHETAS2R14MEN1 | |
| SCHEMBL21724804 | 0.79 | DAO (0.43) | MITFALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |