Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723420 | 0.90 | HSP90AA1 (0.46) | HSP90AA1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21724251 | 0.89 | ALDH1A1 (0.49) | SMN1; SMN2HSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL21723463 | 0.86 | KDM4E (0.49) | TAS2R14ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21723953 | 0.86 | HTT (0.41) | SMN1; SMN2HSP90AA1ALDH1A1KDM4EDBH | |
| SCHEMBL21723721 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2HSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL21723690 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2HSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL21723580 | 0.84 | TSHR (0.47) | HSP90AA1ALDH1A1 | |
| SCHEMBL21723880 | 0.82 | PTPN1 (0.45) | TAS2R14SMN1; SMN2HSP90AA1ALDH1A1MEN1 | |
| SCHEMBL21723648 | 0.80 | ALDH1A1 (0.48) | TAS2R14SMN1; SMN2HSP90AA1ALDH1A1MEN1 | |
| SCHEMBL21724331 | 0.78 | PYCR1 (0.39) | SMN1; SMN2HSP90AA1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |