Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724519 | 0.84 | GAA (0.41) | PKMHTTALDH1A1LMNATSHR | |
| SCHEMBL21723614 | 0.81 | KMT2A (0.38) | HTTALDH1A1LMNAHPGD | |
| SCHEMBL21723936 | 0.81 | GAA (0.49) | PKMHTTALDH1A1LMNATSHR | |
| SCHEMBL21723956 | 0.80 | HTT (0.32) | HTT | |
| SCHEMBL21723841 | 0.79 | LMNA (0.41) | ALDH1A1LMNA | |
| SCHEMBL10852766 | 0.78 | RAB9A (0.46) | ALDH1A1TSHRP2RX7 | |
| SCHEMBL21724706 | 0.78 | CYP1A2 (0.36) | PKMHTTLMNAHPGDP2RX7 | |
| SCHEMBL21723623 | 0.77 | HIF1A (0.31) | P2RX7 | |
| SCHEMBL21724331 | 0.77 | PYCR1 (0.39) | HTTALDH1A1LMNA | |
| SCHEMBL21723951 | 0.77 | PYCR1 (0.48) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |