Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17162566 | 0.87 | CHRM2 (0.39) | KDM4EALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL15440833 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL2733762 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL18116052 | 0.78 | LMNA (0.41) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28601376 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNATSHRCHRM2 | |
| SCHEMBL1961289 | 0.76 | TSHR (0.43) | KDM4EALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL28883097 | 0.75 | LMNA (0.39) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL5248099 | 0.75 | SAT1 (0.46) | ALDH1A1KMT2ARAB9AMEN1NPSR1 | |
| SCHEMBL28356069 | 0.75 | LMNA (0.39) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL22283548 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036211-A1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | 株式会社大分大学先端医学研究所 | 2020-02-20 | — | — | WO | disclosed |