Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.38 |
| ▸ | PPARD | Q03181 | 12/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217585 | 0.84 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL16774833 | 0.81 | S1PR1 (0.39) | PPARAPPARDMAPK11MAPK14S1PR1 | |
| SCHEMBL218708 | 0.80 | MAPK11 (0.43) | PPARAPPARDMAPK11MAPK14S1PR1 | |
| SCHEMBL217240 | 0.80 | PPARA (0.40) | PPARAPPARDMAPK11MAPK14PPARG | |
| SCHEMBL217242 | 0.79 | MAPK11 (0.38) | PPARAPPARDMAPK11MAPK14S1PR1 | |
| SCHEMBL217239 | 0.79 | PPARD (0.40) | PPARAPPARDMAPK11MAPK14PPARG | |
| SCHEMBL217526 | 0.78 | PPARA (0.51) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL217914 | 0.76 | HSD17B1 (0.47) | PPARAPPARDMAPK11MAPK14PPARG | |
| SCHEMBL217328 | 0.74 | PPARA (0.58) | PPARAPPARDPPARGERCC5FEN1 | |
| SCHEMBL217988 | 0.73 | PPARA (0.46) | PPARAPPARDPPARGERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088819-B2 | Derivatives of substituted 3-phenyl-1-(phenylthienyl)propan-1-ones and of 3-phenyl-1-(phenylfuranyl) propan-1-ones, preparation and use | GENFIT (FR) | 2012-01-03 | — | — | US | disclosed |
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | GENFIT (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | TPP1, NAT1, PGC | PPARA 16/4885PPARD 4/4885MAPK11 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.