SCHEMBL21724474

SCHEMBL21724474

CCCC(=O)NC(CC(N)=O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NOD1 Q9Y239 6/20 0.46
ITGB2 P05107 1/20 0.43
ICAM1 P05362 1/20 0.43
ITGAL P20701 1/20 0.43
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
CTSD P07339 1/20 0.42
CA2 P00918 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
CA1 P00915 1/20 0.41
EPHX2 P34913 2/20 0.41
SLC6A5 Q9Y345 2/20 0.40
GNPAT O15228 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25169531 1.00 ECE1 (0.50) ECE1MEN1KMT2ANOD1ITGB2
SCHEMBL21724473 1.00 ECE1 (0.50) ECE1MEN1KMT2ANOD1ITGB2
SCHEMBL31036091 0.89 NOD1 (0.55) ECE1MEN1KMT2ANOD1ALDH1A1
SCHEMBL9664751 0.88 NOD1 (0.62) ECE1MEN1KMT2ANOD1ITGB3
SCHEMBL5273108 0.88 NOD1 (0.62) ECE1MEN1KMT2ANOD1ITGB3
SCHEMBL21724437 0.86 NOD1 (0.65) MEN1KMT2ANOD1ITGB3ITGA2B
SCHEMBL21724210 0.86 NOD1 (0.65) MEN1KMT2ANOD1ITGB3ITGA2B
SCHEMBL7702846 0.86 NOD1 (0.65) MEN1KMT2ANOD1ITGB3ITGA2B
SCHEMBL6536277 0.86 NOD1 (0.65) MEN1KMT2ANOD1ITGB3ITGA2B
SCHEMBL25175260 0.86 NOD1 (0.65) MEN1KMT2ANOD1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250000948-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID ADOCIA (FR) 2025-01-02 US disclosed
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-12-05 US disclosed
EP-4433093-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID Adocia (FR) 2024-09-25 EP disclosed
US-11998610-B2 Conjugates and methods of using the same FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-04 US disclosed
EP-4299057-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID Adocia (FR) 2024-01-03 EP disclosed
WO-2023084118-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID ADOCIA (FR) 2023-05-19 WO disclosed
EP-4180060-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID Adocia (FR) 2023-05-17 EP disclosed
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP disclosed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US disclosed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998610-B2 Conjugates and methods of using the same CD47, CD44, CD74 ECE1 2497/4885MEN1 2346/4885KMT2A 3520/4885
US-20250000948-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID NPPA, BCAT1, ANPEP ECE1 3955/4885MEN1 2101/4885KMT2A 544/4885
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 ECE1 2497/4885MEN1 2346/4885KMT2A 3520/4885
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 ECE1 2497/4885MEN1 2346/4885KMT2A 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.