Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768377 | 0.87 | ADRA2A (0.50) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL1727026 | 0.81 | ALDH1A1 (0.53) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL5460266 | 0.81 | HTR2C (0.46) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL11601509 | 0.81 | HPGD (0.51) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL21736938 | 0.79 | ADRA2A (0.42) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL14236454 | 0.79 | HTR2C (0.50) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL2060735 | 0.79 | MAPT (0.43) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL11144150 | 0.79 | MRGPRX4 (0.44) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL29496131 | 0.79 | LIG1 (0.44) | MAPTL3MBTL1ADRA2AADRA2BADRA2C | |
| SCHEMBL29520257 | 0.79 | MAPT (0.43) | MAPTL3MBTL1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611166-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |