Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544041 | 0.86 | ACHE (0.69) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19979062 | 0.85 | MRGPRX4 (0.47) | ACHEALDH1A1PTGS2HPGDESR1 | |
| SCHEMBL31285761 | 0.83 | MRGPRX4 (0.46) | ACHEKDM4EALDH1A1PTGS2HPGD | |
| SCHEMBL6691258 | 0.82 | MAPK1 (0.49) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL31612517 | 0.82 | MAPK1 (0.49) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29816549 | 0.82 | PTGS2 (0.57) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL198168 | 0.82 | PTGS2 (0.57) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24309423 | 0.81 | HPGD (0.50) | ACHEKDM4EALDH1A1HSD17B10PTGS2 | |
| SCHEMBL6937651 | 0.81 | MAPK1 (0.61) | ACHEMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6194025 | 0.81 | MAPK1 (0.47) | ACHEMAPK1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611166-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |