Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782497 | 0.89 | MAPK1 (0.49) | MAPK1PTPN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL3006462 | 0.88 | KDM4E (0.48) | MAPK1KDM4ETDP1ALDH1A1BLM | |
| SCHEMBL9326165 | 0.86 | KDM4E (0.47) | MAPK1KDM4ETDP1ALDH1A1BLM | |
| SCHEMBL5212814 | 0.86 | MAPK1 (0.71) | MAPK1PTPN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL11224090 | 0.83 | MAPK1 (0.44) | MAPK1PTPN1TDP1KMT2AMAPT | |
| SCHEMBL10499349 | 0.83 | LMNA (0.48) | MAPK1KDM4ETDP1ALDH1A1BLM | |
| SCHEMBL6691258 | 0.82 | MAPK1 (0.49) | MAPK1PTPN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL31612517 | 0.82 | MAPK1 (0.49) | MAPK1PTPN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL29816549 | 0.82 | PTGS2 (0.57) | MAPK1KDM4ETDP1ALDH1A1BLM | |
| SCHEMBL198168 | 0.82 | PTGS2 (0.57) | MAPK1KDM4ETDP1ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101538542-B | Pseudomonad esterase and application in preparing optical pure mandel and derivative thereof | UNIV EAST CHINA SCIENCE & TECH | 2010-12-29 | — | — | CN | disclosed |
| CN-101538542-A | Pseudomonad esterase and application in preparing optical pure mandel and derivative thereof | UNIV EAST CHINA SCIENCE & TECH | 2009-09-23 | — | — | CN | disclosed |
| CN-1190441-C | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2005-02-23 | — | — | CN | disclosed |
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |