Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21728194 | 0.94 | PGR (0.35) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21728308 | 0.93 | SLC6A2 (0.35) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21728107 | 0.93 | SLC6A2 (0.35) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21728119 | 0.93 | SLC6A2 (0.35) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21728485 | 0.92 | L3MBTL1 (0.36) | HSD11B1SLC6A2SLC6A4SLC6A3NR1I2 | |
| SCHEMBL21728291 | 0.91 | HSD11B1 (0.33) | PGRHSD11B1NR1I2ALDH1A1L3MBTL1 | |
| SCHEMBL21728297 | 0.90 | PGR (0.39) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21728300 | 0.88 | PGR (0.32) | PGRHSD11B1NR1I2 | |
| SCHEMBL21728203 | 0.88 | PGR (0.32) | PGRHSD11B1NR1I2 | |
| SCHEMBL21728448 | 0.86 | MEN1 (0.39) | PGRHSD11B1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214084-B1 | CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-19 | — | — | EP | disclosed |