Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179861 | 0.79 | BAZ2B (0.46) | KDM4EPSMB8PSMB9PSMB5SMN1; SMN2 | |
| SCHEMBL10044972 | 0.76 | GRIA1 (0.34) | KDM4E | |
| SCHEMBL903084 | 0.76 | GAA (0.50) | KDM4EMAPTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL18179934 | 0.75 | ALDH1A1 (0.40) | KDM4EPSMB8PSMB9PSMB5MAPT | |
| SCHEMBL12343345 | 0.72 | PTGS2 (0.47) | MAPTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL3700954 | 0.72 | HTT (0.52) | KDM4ETP53HPGD | |
| SCHEMBL13184429 | 0.72 | HPGD (0.60) | KDM4EMAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL2938277 | 0.71 | PTGS2 (0.35) | KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL14154659 | 0.71 | MEN1 (0.45) | KDM4ECYP1A2LMNA | |
| SCHEMBL1412553 | 0.69 | TP53 (0.56) | KDM4EMAPTSMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |