Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12537977 | 1.00 | POLB (0.48) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL3825600 | 0.86 | POLB (0.48) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL21983964 | 0.80 | LMNA (0.55) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL21728893 | 0.79 | MEN1 (0.53) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL520997 | 0.77 | CA2 (0.47) | POLBLMNAHTTMEN1KMT2A | |
| SCHEMBL29217918 | 0.77 | ALDH1A1 (0.52) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL24456745 | 0.75 | EPAS1 (0.59) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL11409224 | 0.75 | ALDH1A1 (0.50) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL13556573 | 0.75 | ALDH1A1 (0.70) | POLBALDH1A1EPAS1LMNAHTT | |
| SCHEMBL12537974 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |