SCHEMBL21728959

SCHEMBL21728959

C=CC(=O)NCCCCCCNC(=O)C(=O)OCC

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.64
ZDHHC2 Q9UIJ5 2/20 0.64
EGLN1 Q9GZT9 1/20 0.47
TGM2 P21980 5/20 0.47
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.38
EPHX1 P07099 3/20 0.37
FAAH O00519 1/20 0.36
EPHX2 P34913 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2032859 0.86 EGLN1 (0.61) EGLN1MAPK1EPHX1FAAHKDM4E
SCHEMBL11596790 0.86 EGLN1 (0.61) EGLN1MAPK1EPHX1FAAHKDM4E
SCHEMBL13552393 0.84 EGLN1 (0.63) EGLN1MAPK1ALDH1A1GAAEPHX1
SCHEMBL22382274 0.83 ZDHHC20 (0.69) ZDHHC20ZDHHC2TGM2TSHREPHX1
SCHEMBL18808391 0.83 ZDHHC20 (0.53) ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1
SCHEMBL11793603 0.82 ZDHHC20 (0.62) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
SCHEMBL11408936 0.80 EPHX1 (0.57) ZDHHC20ZDHHC2EGLN1TSHREPHX1
SCHEMBL2487820 0.80 EPHX1 (0.57) ZDHHC20ZDHHC2EGLN1TSHREPHX1
SCHEMBL15682714 0.80 EPHX1 (0.57) ZDHHC20ZDHHC2EGLN1TSHREPHX1
SCHEMBL270209 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TGM2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547674-B2 Protein-polymer hybrid biomaterials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-01-10 US disclosed
US-20200054574-A1 PROTEIN-POLYMER HYBRID BIOMATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054574-A1 PROTEIN-POLYMER HYBRID BIOMATERIALS LDHA, LDHB, STIP1 ZDHHC20 2381/4885ZDHHC2 2641/4885EGLN1 323/4885
US-11547674-B2 Protein-polymer hybrid biomaterials LDHA, LDHB, STIP1 ZDHHC20 2381/4885ZDHHC2 2641/4885EGLN1 323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.