Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680163 | 0.92 | — | — | |
| SCHEMBL364269 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL490234 | 0.84 | — | — | |
| SCHEMBL6946157 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL28548326 | 0.81 | NCF1 (0.40) | LMNAHTTALDH1A1NCF1POLB | |
| Ammonia Solution, Strong SCHEMBL27534524 | 0.81 | NCF1 (0.40) | LMNAHTTALDH1A1NCF1POLB | |
| Magnesium Chloride Anhydrous SCHEMBL28548324 | 0.79 | NCF1 (0.39) | LMNAHTTALDH1A1NCF1POLB | |
| SCHEMBL10287120 | 0.72 | ACHE (0.41) | LMNAHTTALDH1A1NCF1SIGMAR1 | |
| SCHEMBL2905100 | 0.72 | — | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL37881 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020037251-A1 | BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS TO TREAT MEDICAL DISORDERS | G1 THERAPEUTICS, INC. (US) | 2020-02-20 | — | — | WO | disclosed |