⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364269 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL490234 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL28548326 | 0.91 | NCF1 (0.40) | — | |
| Ammonia Solution, Strong SCHEMBL27534524 | 0.91 | NCF1 (0.40) | — | |
| Magnesium Chloride Anhydrous SCHEMBL28548324 | 0.88 | NCF1 (0.39) | — | |
| SCHEMBL10680163 | 0.86 | — | — | |
| SCHEMBL21729982 | 0.84 | LMNA (0.42) | — | |
| SCHEMBL9699113 | 0.79 | — | — | |
| SCHEMBL140205 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL7853639 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402105-A | Preparation method of cyproheptadine hydrochloride | 云鹏医药集团有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-110407737-B | Preparation method of cyproheptadine hydrochloride | 广州普星药业有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-117402105-A | Preparation method of cyproheptadine hydrochloride | 云鹏医药集团有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117402105-A | Preparation method of cyproheptadine hydrochloride | 云鹏医药集团有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-110407737-B | Preparation method of cyproheptadine hydrochloride | 广州普星药业有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-100345843-C | 4- (thioxanthene-9-subunit) -piperidine or acridine derivative and application thereof in preparation of medicines | BIOFRONTERA PHARMACEUTICALS GM (DE) | 2007-10-31 | — | — | CN | disclosed |
| CN-1575291-A | Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-ht2b receptor antagonist | BIOFRONTERA PHARMACEUTICALS GM (DE) | 2005-02-02 | — | — | CN | disclosed |
| EP-1140899-B1 | PROCESS FOR PREPARING TRICYCLIC COMPOUNDS HAVING ANTIHISTAMINIC ACTIVITY | SCHERING CORP (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6440989-B2 | ANTITUMOR AGENT | SCHERING CORPORATION | 2002-08-27 | — | — | US | disclosed |
| EP-1140899-A1 | PROCESS FOR PREPARING TRICYCLIC COMPOUNDS HAVING ANTIHISTAMINIC ACTIVITY | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| US-20010016585-A1 | Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase | AFONSO ADRIANO (IN) | 2001-08-23 | — | — | US | disclosed |
| WO-1989010369-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| US-4843163-A | Certain 3-(2-phenethyl)-1-carbamoyloxypyridinium halide intermediates | SMITHKLINE BECKMAN CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0319254-A2 | Intermediates for the production of pyridobenzocycloheptene | SMITHKLINE BEECHAM CORPORATION (US) | 1989-06-07 | — | — | EP | disclosed |
| EP-0000716-B1 | PYRROLO(2,1-B)(3)BENZAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1983-03-09 | — | — | EP | disclosed |
| US-4195091-A | Appetite stimulating pyrrolo[2,1-b][3]benzazepines | MERCK & CO., INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4148903-A | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines | MERCK & CO., INC. (US) | 1979-04-10 | — | — | US | disclosed |
| EP-0000716-A2 | Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1979-02-21 | — | — | EP | disclosed |
| US-4020169-A | FROM ARYL IODIDE OR BROMIDE AND TRIFLUOROMETHYL THIO COPPER | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |
| US-3981877-A | APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |