Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678472 | 0.88 | ALDH1A1 (0.46) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL22477463 | 0.88 | ALDH1A1 (0.46) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL5706327 | 0.87 | RXRA (0.51) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL26606993 | 0.87 | RXRA (0.51) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL6278724 | 0.85 | RXRA (0.41) | RXRARXRBRXRGALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL28596997 | 0.84 | RXRA (0.40) | RXRARXRBRXRGHPGDHSD17B10 | |
| SCHEMBL6281772 | 0.81 | RXRA (0.50) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL8308844 | 0.79 | RXRA (0.43) | RXRARXRBRXRGPRKCD | |
| SCHEMBL6507886 | 0.79 | RXRA (0.40) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL6711237 | 0.78 | ALDH1A1 (0.46) | RXRARXRBRXRGALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020037246-A1 | DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-02-20 | — | — | WO | disclosed |