Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496263 | 0.88 | FTO (0.43) | RXRAFTOHSD17B1ESR1CYP19A1 | |
| SCHEMBL21730005 | 0.84 | RXRA (0.44) | RXRARXRBRXRGHPGDHSD17B10 | |
| SCHEMBL4233115 | 0.81 | FTO (0.40) | RXRAFTOHSD17B1ESR1CYP19A1 | |
| SCHEMBL26606993 | 0.79 | RXRA (0.51) | RXRARXRBRXRGESR1CYP19A1 | |
| SCHEMBL5706327 | 0.76 | RXRA (0.51) | RXRARXRBRXRGESR1CYP19A1 | |
| SCHEMBL6278724 | 0.75 | RXRA (0.41) | RXRARXRBRXRGHSD17B1CYP19A1 | |
| SCHEMBL30250372 | 0.74 | ESR2 (0.51) | RXRARXRBRXRGESR1DRD2 | |
| SCHEMBL1495864 | 0.74 | ESR2 (0.51) | RXRARXRBRXRGESR1DRD2 | |
| SCHEMBL22477463 | 0.72 | ALDH1A1 (0.46) | RXRARXRBRXRGESR1HPGD | |
| SCHEMBL8678472 | 0.72 | ALDH1A1 (0.46) | RXRARXRBRXRGESR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573872-B | 5-hydroxytryptamine receptor targeting compounds and methods | 东北大学 | 2021-07-20 | — | — | CN | disclosed |