Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11960340 | 0.86 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL30695179 | 0.79 | ALDH1A1 (0.39) | SIGMAR1 | |
| SCHEMBL18951468 | 0.78 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL28211897 | 0.76 | MAPK1 (0.32) | — | |
| SCHEMBL16287326 | 0.76 | — | — | |
| SCHEMBL18295756 | 0.75 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL16845264 | 0.75 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL15128022 | 0.74 | — | — | |
| SCHEMBL16288149 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL14074643 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346334-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010036544-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |