SCHEMBL21732329

SCHEMBL21732329

Cc1cccc(-c2cccc(C)[n+]2C)[n+]1C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 1/20 0.40
KCNH2 Q12809 6/20 0.33
ACHE P22303 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CD44 P16070 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1277062 0.84
SCHEMBL26075761 0.84 HDAC8 (0.40) KDM4ESMN1; SMN2HTTACHEMAPT
SCHEMBL25445609 0.83 CD44 (0.39) KDM4ESMN1; SMN2HTTACHECD44
Iodide SCHEMBL28884004 0.81 SMN1; SMN2 (0.38) KDM4ESMN1; SMN2HTTKCNH2ACHE
Water SCHEMBL22654522 0.81 ACHE (0.35) KDM4ESMN1; SMN2HTTKCNH2ACHE
Bromide SCHEMBL27774766 0.81 SMN1; SMN2 (0.36) KDM4ESMN1; SMN2HTTKCNH2ACHE
SCHEMBL25447006 0.79 SMN1; SMN2 (0.36) KDM4ESMN1; SMN2HTTKCNH2ACHE
SCHEMBL25447081 0.78 TRPA1 (0.35) KDM4ESMN1; SMN2HTTCD44CYP1A2
SCHEMBL26716643 0.78 TDP2 (0.33) KDM4ESMN1; SMN2HTTCD44
SCHEMBL25445618 0.76 MAPT (0.37) KDM4ESMN1; SMN2HTTKCNH2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024013006-A1 CROSSLINKABLE FLUOROPOLYMER COMPOSITIONS FOR SEALING FUEL CELLS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-01-18 WO disclosed
EP-3941974-B1 FLUOROELASTOMER COMPOSITION SOLVAY SPECIALTY POLYMERS IT (IT) 2023-11-08 EP disclosed
US-20200056064-A1 COATING COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2020-02-20 US disclosed