SCHEMBL21732692

SCHEMBL21732692

CCOC(=O)CCSP(=O)(OC(C)C)OC(C)CSP(=O)(OC(C)CSP(=O)(OC(C)C)OC(C)C)OC(C)CSP(=O)(OC(C)C)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP1A2 P05177 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21732467 1.00 ALOX15 (0.35) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL21732719 0.95 ALOX15 (0.32) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL25670495 0.92 ALOX15 (0.31) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL21732699 0.92 ALOX15 (0.31) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL28699754 0.91 ALDH1A1 (0.40) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL25670400 0.91 ALOX15 (0.32) ALOX15
SCHEMBL21732709 0.90 ALOX15 (0.34) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL21732707 0.87 ALOX15 (0.32) ALOX15TSHRALDH1A1TDP1CYP3A4
SCHEMBL21732898 0.86 TSHR (0.34) TSHRALDH1A1
SCHEMBL21732712 0.86 TSHR (0.34) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667866-B2 Phosphorous containing compounds and uses thereof AFTON CHEMICAL CORPORATION (US) 2023-06-06 US disclosed
US-11667866-B2 Phosphorous containing compounds and uses thereof AFTON CHEMICAL CORPORATION (US) 2023-06-06 US disclosed
US-20210355408-A1 Phosphorous Containing Compounds and Uses Thereof AFTON CHEMICAL CORP (US) 2021-11-18 US disclosed
US-11066619-B2 Phosphorous containing compounds and uses thereof AFTON CHEMICAL CORPORATION (US) 2021-07-20 US disclosed
US-20200056114-A1 Phosphorous Containing Compounds and Uses Thereof AFTON CHEMICAL CORP (US) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355408-A1 Phosphorous Containing Compounds and Uses Thereof SOST, PHOSPHO1, PSPH ALOX15 735/4885TSHR 4882/4885ALDH1A1 4608/4885
US-20200056114-A1 Phosphorous Containing Compounds and Uses Thereof SOST, PHOSPHO1, PSPH ALOX15 735/4885TSHR 4882/4885ALDH1A1 4608/4885
US-11667866-B2 Phosphorous containing compounds and uses thereof SOST, PHOSPHO1, PSPH ALOX15 735/4885TSHR 4882/4885ALDH1A1 4608/4885
US-11066619-B2 Phosphorous containing compounds and uses thereof SOST, PHOSPHO1, PSPH ALOX15 735/4885TSHR 4882/4885ALDH1A1 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.