Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441726 | 0.84 | FPR2 (0.37) | FPR3FPR2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21133701 | 0.78 | ALDH1A1 (0.33) | ALDH1A1POLBL3MBTL1KDM4ELMNA | |
| SCHEMBL19263785 | 0.77 | ALDH1A1 (0.31) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21133449 | 0.77 | — | — | |
| SCHEMBL21733114 | 0.75 | — | — | |
| SCHEMBL21733027 | 0.73 | FPR3 (0.34) | FPR3FPR2 | |
| SCHEMBL22041026 | 0.73 | — | — | |
| SCHEMBL21133516 | 0.73 | KDM4E (0.30) | ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL21732965 | 0.68 | ALDH1A1 (0.39) | FPR3FPR2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL13852640 | 0.66 | MEN1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3254678-B1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2020-02-19 | — | — | EP | disclosed |