Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405114 | 0.82 | HSD17B10 (0.38) | TSHRALDH1A1 | |
| SCHEMBL12752046 | 0.79 | TSHR (0.33) | TSHRALDH1A1ACHE | |
| SCHEMBL13876695 | 0.79 | ACHE (0.39) | TSHRALDH1A1ACHECHRNB2CHRNB4 | |
| SCHEMBL15521662 | 0.79 | ACHE (0.39) | TSHRALDH1A1ACHECHRNB2CHRNB4 | |
| SCHEMBL786190 | 0.79 | ACHE (0.39) | TSHRALDH1A1ACHECHRNB2CHRNB4 | |
| SCHEMBL12893358 | 0.79 | TSHR (0.38) | TSHRALDH1A1ACHECHRNB2CHRNB4 | |
| SCHEMBL24242053 | 0.79 | TSHR (0.45) | TSHRALDH1A1 | |
| SCHEMBL445640 | 0.79 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL17635142 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1ACHE | |
| SCHEMBL445678 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3254678-B1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2020-02-19 | — | — | EP | disclosed |