Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502908 | 0.80 | SIRT2 (0.38) | ALDH1A1MAPTGAASIRT2IDO1 | |
| SCHEMBL13256759 | 0.80 | SIRT2 (0.38) | ALDH1A1MAPTGAASIRT2IDO1 | |
| SCHEMBL29556882 | 0.80 | SIRT2 (0.38) | ALDH1A1MAPTGAASIRT2IDO1 | |
| SCHEMBL7024893 | 0.79 | MAPT (0.41) | ALDH1A1MAPTGAASIRT2GOT1 | |
| SCHEMBL12704676 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTGAASIRT2GOT1 | |
| SCHEMBL31521355 | 0.76 | MAPT (0.39) | ALDH1A1MAPTGAASIRT2GOT1 | |
| SCHEMBL15994699 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTGAASIRT2GOT1 | |
| SCHEMBL21539326 | 0.75 | CCNE2 (0.39) | SIRT2SMN1; SMN2LMNAMEN1POLB | |
| SCHEMBL20354954 | 0.75 | APP (0.45) | MAPTGAASIRT2TDP1SMN1; SMN2 | |
| SCHEMBL30657526 | 0.75 | PGK1 (0.39) | SIRT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402797-B1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-02-19 | — | — | EP | disclosed |