Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21733183 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15294527 | 0.77 | MAPT (0.38) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31521355 | 0.77 | MAPT (0.39) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15994699 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1GAAGOT1TDP1 | |
| SCHEMBL12704676 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1GAAPOLBKDM4E | |
| SCHEMBL4375478 | 0.73 | MAPT (0.41) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8135420 | 0.73 | MAPT (0.41) | MAPTALDH1A1GAAKMT2APOLB | |
| SCHEMBL28226026 | 0.71 | CRHBP (0.35) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL19093153 | 0.70 | KMT2A (0.41) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28782731 | 0.70 | KMT2A (0.41) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552284-B | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-112552284-A | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-107778225-A | A kind of preparation method of the chloropyridine of 2 diazanyl 3 | 上海雅本化学有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-118791428-A | Method for preparing 3-chloro-2-hydrazinopyridine | 利尔化学股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-117945991-A | Novel synthetic method of 3-chloro-2-hydrazinopyridine | 浙江工业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-114057632-B | Environment-friendly synthesis method of 3-chloro-2-hydrazinopyridine | 苏州开元民生科技股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-112552284-B | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112552284-B | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114057632-A | Environment-friendly synthesis method of 3-chloro-2-hydrazinopyridine | 苏州开元民生科技股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-112552284-A | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112552284-A | Preparation method of chlorantraniliprole | 重庆华歌生物化学有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-10329280-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| CN-107778225-A | A kind of preparation method of the chloropyridine of 2 diazanyl 3 | 上海雅本化学有限公司 | 2018-03-09 | — | — | CN | disclosed |
| WO-2014126580-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-0930300-B1 | Process for preparing (poly)chloropyridines | DAICEL CHEM (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5977370-A | Process for preparing pyridine chloride | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0930300-A1 | Process for preparing (poly)chloropyridines | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329280-B2 | Urea derivatives and uses thereof | UACA, RB1, FLT1 | MAPT 1024/4885ALDH1A1 1432/4885GAA 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.