Sugi Predict

Sugi Predict / Compounds / SCHEMBL21733207

SCHEMBL21733207

SCHEMBL21733207

C[C@H](c1ccccc1)C1CCC[C@@H]1P(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.38
▸ MCOLN3 Q8TDD5 1/20 0.38
▸ GAA P10253 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ RECQL P46063 1/20 0.36
▸ CYP2D6 P10635 2/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ CHRNB4 P30926 1/20 0.32
▸ CHRNA3 P32297 1/20 0.32
▸ USP2 O75604 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ EPHX1 P07099 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17470033 0.85 HIF1A (0.37) GAAL3MBTL1RECQLCYP2D6CYP1A2
SCHEMBL19286298 0.85 HIF1A (0.37) GAAL3MBTL1RECQLCYP2D6CYP1A2
SCHEMBL13150731 0.85 KCNA5 (0.33) ALDH1A1GAAL3MBTL1RECQLMEN1
SCHEMBL18652525 0.82 GAA (0.31) GAAL3MBTL1RECQL
SCHEMBL15684660 0.82 HTR2A (0.32) GAAL3MBTL1RECQL
SCHEMBL6264931 0.82 GAA (0.31) GAAL3MBTL1RECQL
SCHEMBL13421750 0.82 HTR2A (0.32) GAAL3MBTL1RECQL
SCHEMBL6264929 0.82 GAA (0.31) GAAL3MBTL1RECQL
SCHEMBL17470036 0.82 HTR2A (0.32) GAAL3MBTL1RECQL
SCHEMBL16317619 0.82 KDM4E (0.32) ALDH1A1GAAL3MBTL1RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds BASF SE (DE) 2021-09-21 — — US disclosed
US-20210087207-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-03-25 — — US disclosed
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds BASF SE (DE) 2020-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds UMPS, UGP2, UGT1A4 ALDH1A1 56/4885MCOLN3 2739/4885GAA 632/4885
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds UMPS, UGP2, UGT1A4 ALDH1A1 56/4885MCOLN3 2739/4885GAA 632/4885
US-20210087207-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS UMPS, UGP2, XDH ALDH1A1 123/4885MCOLN3 3941/4885GAA 784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.