Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21733824 | 0.89 | MAPT (0.36) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24854884 | 0.86 | KDM4E (0.32) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL21733838 | 0.81 | TP53 (0.32) | ALDH1A1 | |
| SCHEMBL26268266 | 0.81 | TP53 (0.32) | ALDH1A1 | |
| SCHEMBL21733627 | 0.81 | TP53 (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL24854893 | 0.75 | KDM4E (0.32) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL26268285 | 0.74 | ALDH1A1 (0.40) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24855041 | 0.73 | KDM4E (0.34) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL28490711 | 0.73 | TUBB3 (0.33) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL26269144 | 0.72 | TP53 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |