Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21734001 | 0.81 | NOS1 (0.32) | NOS1 | |
| SCHEMBL21733602 | 0.75 | NOS1 (0.31) | NOS1 | |
| SCHEMBL18408609 | 0.72 | — | — | |
| SCHEMBL20970353 | 0.67 | CHRM2 (0.30) | — | |
| SCHEMBL23841341 | 0.67 | CDK2 (0.34) | — | |
| SCHEMBL12110234 | 0.65 | METAP2 (0.46) | NOS1 | |
| SCHEMBL17030759 | 0.65 | IDO1 (0.41) | NOS1 | |
| SCHEMBL20132917 | 0.64 | IDO1 (0.40) | NOS1 | |
| SCHEMBL20510113 | 0.63 | IDO1 (0.39) | NOS1 | |
| SCHEMBL25906933 | 0.61 | NR3C1 (0.35) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |