Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793933 | 0.83 | ACMSD (0.53) | ACMSDTDP1PSMB5CYP3A4JAK2 | |
| SCHEMBL27359997 | 0.80 | MAPT (0.53) | LMNAMAPTMAPK14CYP3A4CYP2C9 | |
| SCHEMBL2171290 | 0.78 | PPARA (0.57) | LMNAMAPTTDP1PPARACYP3A4 | |
| SCHEMBL17721315 | 0.77 | PPARA (0.56) | LMNAMAPTTDP1PPARACYP3A4 | |
| SCHEMBL191429 | 0.76 | ACMSD (0.49) | ACMSDTDP1SIGMAR1PTGS2 | |
| SCHEMBL8380044 | 0.76 | ACMSD (0.49) | ACMSDTDP1SIGMAR1PTGS2 | |
| SCHEMBL12879148 | 0.75 | ADRB2 (0.46) | KDRACMSDTDP1PSMB5PPARA | |
| SCHEMBL16188025 | 0.75 | PSMB5 (0.46) | KDRACMSDTDP1PSMB5CASP3 | |
| SCHEMBL15465713 | 0.75 | HDAC1 (0.43) | KDRACMSDTDP1PSMB5JAK2 | |
| SCHEMBL27572022 | 0.75 | ACMSD (0.42) | KDRACMSDTDP1PSMB5JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | claimed |
| EP-4141980-A1 | ORGANIC LIGHT EMITTING DIODE AND A COMPOUND FOR USE THEREIN | Novaled GmbH (DE) | 2023-03-01 | — | — | EP | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. | 2015-02-19 | — | — | US | disclosed |
| US-8906925-B2 | Pyrido[4,3-B]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906925-B2 | Pyrido[4,3-B]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2010051501-A1 | PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010051501-A1 | PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| CN-1335836-A | Tricyclic pyrazole derivatives | BASF AG (DE) | 2002-02-13 | — | — | CN | disclosed |
| US-4727148-A | Certain aromatization process for preparing 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4727148-A | Certain aromatization process for preparing 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4604467-A | Certain 4-(3,4-dibromocyclohexyl)pyridines | ETHYL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4604467-A | Certain 4-(3,4-dibromocyclohexyl)pyridines | ETHYL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | HTR3B, HTR3D, HTR3A | KDR 4310/4885LMNA 3212/4885MAPT 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.