Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735267 | 0.90 | CYP2E1 (0.32) | — | |
| SCHEMBL21735214 | 0.87 | HDAC6 (0.38) | HDAC6FFAR1MMP12MMP13PTGS2 | |
| SCHEMBL22628735 | 0.87 | HDAC6 (0.38) | HDAC6FFAR1MMP12MMP13KLK7 | |
| SCHEMBL21734934 | 0.87 | HDAC6 (0.36) | HDAC6FFAR1MMP12MMP13PTGS2 | |
| SCHEMBL21734928 | 0.84 | NPC1 (0.38) | HDAC6KLK7 | |
| SCHEMBL21735307 | 0.81 | — | — | |
| SCHEMBL21735311 | 0.79 | HDAC6 (0.36) | HDAC6FFAR1PTGS2KLK7 | |
| SCHEMBL21735735 | 0.78 | HDAC6 (0.38) | HDAC6FFAR1MMP12MMP13PTGS2 | |
| SCHEMBL21735240 | 0.78 | HDAC6 (0.37) | HDAC6FFAR1PTGS2KLK7 | |
| SCHEMBL21735062 | 0.78 | HDAC6 (0.37) | HDAC6FFAR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | HDAC6 1975/4885FFAR1 1590/4885MMP12 3480/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | HDAC6 1975/4885FFAR1 1590/4885MMP12 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.